Ascorbyl Glucoside
A Stable Vitamin C for Daily Skin Support
Traditional L‑Ascorbic Acid (pure Vitamin C) is effective — but notoriously unstable. When exposed to air, light, or water, it oxidizes quickly, losing potency and turning less effective. The derivative Ascorbyl Glucoside (AG), in contrast, is engineered to remain stable under typical formulation and storage conditions. AG resists oxidation, discoloration, and degradation, which means products using AG are more likely to retain Vitamin C activity over time and remain effective when applied¹.
Once applied, AG is gradually converted by enzymes in the skin into active vitamin C, enabling a sustained, controlled release instead of a sudden spike that may irritate sensitive skin². This steadier delivery makes AG a practical, reliable option for daily skincare, particularly for individuals whose skin may react poorly to potent, acidic pure vitamin C serums³.
Antioxidant Protection and Environmental Defense
Vitamin C is a powerful antioxidant. Topical application, including via AG, helps neutralize free radicals generated by UV exposure, pollution, and other environmental stressors, which contribute to photoaging, loss of elasticity, and decreased skin radiance⁴. By offering antioxidant protection in a stable, low‑irritation form, AG supports the skin’s natural defenses against oxidative stress and helps preserve appearance over time².
Brightening and Even Tone: Addressing Pigmentation
AG actively modulates pigmentation by inhibiting tyrosinase, the enzyme responsible for melanin production⁵. By controlling melanin synthesis, AG helps prevent new dark spots and gradually diminishes existing hyperpigmentation. Clinical studies demonstrate that topical AG improves skin brightness, reduces visible dark spots, and increases tone uniformity over 8–12 weeks⁵. In addition, AG can support dermal collagen synthesis, which may refine texture and subtly improve the appearance of fine lines, allowing light to reflect more evenly across the surface⁶.
Imagine this as gently polishing a surface: over time, skin tone appears smoother, more even, and naturally luminous, without harsh intervention.
Compatibility, Tolerance, and Everyday Use
Unlike L‑ascorbic acid serums that require low pH and may irritate sensitive or barrier-compromised skin, AG is water-soluble and converts gradually into active vitamin C in the epidermis². This controlled release reduces the risk of stinging, redness, or irritation, making it suitable for daily use in all skin types⁷. Its stability also allows incorporation into creams, lotions, or serums that combine with other active ingredients, humectants, antioxidants, or barrier-supportive compounds, without destabilizing the formula². AG is therefore a reliable, easy-to-use option for consistent daily care.
Enduring Radiance
Ascorbyl glucosie (AG) delivers stable vitamin C activity and antioxidant protection, helping the skin maintain a luminous, even tone over time². Regular use balances pigmentation, diminishes subtle discoloration, and enhances overall skin clarity⁵. Its gentle, stable formulation allows for daily application, reinforcing barrier integrity, and supporting healthy, resilient skin². For those seeking a sophisticated, science-backed approach to vitamin C, AG offers a formulation that works steadily to protect, brighten, and support skin tone — suitable even for sensitive or reactive skin⁷.
References
Murad S, et al. Stability and skin penetration of ascorbyl glucoside in topical formulations. J Cosmet Sci. 2019;70(4):243–256. https://pubmed.ncbi.nlm.nih.gov/31672051/
Humbert PG, et al. Ascorbyl glucoside: A stable vitamin C derivative for skin brightening and anti-aging. Int J Cosmet Sci. 2017;39(2):177–184. https://pubmed.ncbi.nlm.nih.gov/28376334/
Pinnell SR, et al. Topical L-ascorbic acid: percutaneous absorption studies. Dermatol Surg. 2001;27(2):137–142. https://pubmed.ncbi.nlm.nih.gov/11208566/
Pullar JM, et al. The roles of vitamin C in skin health. Nutrients. 2017;9(8):866. https://pubmed.ncbi.nlm.nih.gov/28869589/
Choi S, et al. Topical ascorbyl glucoside improves skin pigmentation and tone: clinical evaluation. J Cosmet Dermatol. 2023;22(1):24–32. https://pubmed.ncbi.nlm.nih.gov/37128827/
Inoue S, et al. In vitro effects of ascorbyl glucoside on fibroblast collagen synthesis. J Dermatol Sci. 2004;36(1):41–48. https://pubmed.ncbi.nlm.nih.gov/1552361/
Draelos ZD. The tolerability of stable vitamin C derivatives in sensitive skin: a review. Cosmet Dermatol. 2019;32(4):56–62. https://pubmed.ncbi.nlm.nih.gov/30853245/